On the Mechanism of N-Heterocyclic Carbene-Catalyzed …
Jan 10, 2014 · These new NHC-catalyzed reactions allow chemists to generate unique reactive species from otherwise inert starting materials, all under simple, mild reaction conditions and with exceptional selectivities.
Recent advances in N-heterocyclic carbene-catalyzed radical …
Feb 1, 2021 · The N-heterocyclic carbene (NHC)-catalyzed reactions involving two-electron reaction pathway have been well-established. However, the development of NHC-catalyzed radical reactions is still in its infancy in terms of reaction types and enantioselectivity.
Aryl radical-mediated N-heterocyclic carbene catalysis
Jun 22, 2021 · In this article, the NHC organocatalysis mediated by aryl radicals has been achieved. The enolate form of the Breslow intermediate derived from an aldehyde and thiazolium-type NHC in the presence...
Cobalt–N-Heterocyclic Carbene Complexes in Catalysis
Feb 21, 2022 · Cobalt–N-heterocyclic carbene (NHC) complexes have emerged as an attractive class of 3d transition metal catalysts for a broad range of chemical processes, including cross-coupling, hydrogenation, hydrofunctionalization, and cycloaddition reactions.
N-Heterocyclic carbene-catalyzed dimerization, cyclotetramerization …
Aug 12, 2015 · In this focused review, the NHC-catalyzed transformations of Michael acceptors developed by our research group, including tail-to-tail dimerization, 44, 45, 46, 47 cyclotetramerization 48 and...
Oxidative Amidation and Azidation of Aldehydes by NHC Catalysis
Apr 1, 2010 · N-Heterocyclic carbene catalyzed oxidative amidations of various aldehydes to the corresponding hexafluoroisopropylesters by using the readily available organic oxidant A are described. The hexafluoroisopropylesters prepared in situ are shown to be highly useful active esters for amide bond formation.
NHC-Catalyzed Reaction of Aldehydes for C(sp 2 )–O Bond …
Mar 22, 2024 · In the past few decades, N-heterocyclic carbenes (NHCs) have opened the new field of organocatalysis in synthetic organic chemistry. This review highlights the dramatic progress in the field of NHC-catalyzed C–O bond formation based on the activation of aldehyde C(sp2)–H bonds.
Asymmetric reactions of N-heterocyclic carbene (NHC)-based chiral …
May 1, 2021 · In this review, we will cover the generation and application of acyl azoliums and azolium enolates 2B-G on asymmetric transformations catalyzed by NHCs since 2010. This summary is organized based on the types of acyl azoliums and azolium enolates.
DFT investigation of the mechanism and role of N-heterocyclic …
May 18, 2024 · Herein, DFT computations of the NHC-catalyzed [4+2] cycloaddition reaction between R1 and R2 have been performed, as shown in Scheme 3. This study aims to describe the potential role of N-heterocyclic carbene (NHC) as an organocatalyst in promoting [4+2] cycloaddition reactions with a deep insight and a broad understanding of their important ...
azolium-NHC-catalyzed method for the aerobic oxidation of aldehydes to the corresponding carboxylic acids under mild conditions in a short reaction time. More significantly, this method is suitable for several classes of challenging al-dehydes such as ortho-substituted aryl aldehydes, highly electron-rich aryl aldehydes and indole-3 ...