Sphingolipids and their metabolism in physiology and disease
Nov 22, 2017 · Taken together, these studies begin to define several causal roles for sphingolipids in normal brain functions and as mediators of neuronal damage and neurodegenerative disorders.
Sphingolipid - an overview | ScienceDirect Topics
Sphingolipids are a class of lipids characterised by the presence of a sphingosine backbone. This includes a range of lipids including ceramide, sphingosine and sphingomyelin. A range of different cellular functions for sphingolipids have been described. Sphingolipids are a key structural component for membranes, including lipid rafts [57].
Regulation of cellular and systemic sphingolipid homeostasis
Jun 18, 2024 · Sphingolipids are a heterogeneous group of lipids with important roles in membrane form and function, cell signalling, and development.
An overview of sphingolipid metabolism: from synthesis to …
Sphingolipids are a diverse group of lipids which serve a variety of functions in both mammalian development and physiology. Only a few of these functions have been highlighted in the chapter, but the scope of sphingolipid biology is vast.
Sphingolipid – Definition, Structure, Types, Functions
Apr 1, 2024 · Some of the key functions of sphingolipids include: Cell Signaling: Sphingolipids act as crucial mediators of cellular signaling pathways. Ceramides, in particular, play a significant role in regulating cell growth, differentiation, and apoptosis (programmed cell death).
Functional roles of sphingolipids in immunity and their …
Jun 1, 2023 · Sphingolipids, which are components of cellular membranes and organ tissues, can be synthesized or degraded to modulate cellular responses according to environmental cues, and the balance among...
Sphingolipid Metabolic Pathway: An Overview of Major Roles …
Sphingolipids, a family of membrane lipids, are bioactive molecules that participate in diverse functions controlling fundamental cellular processes such as cell division, differentiation, and cell death.
1.5: Sphingolipids - Physics LibreTexts
There are many biological functions associated with sphingolipids, including cellular regulation, signaling and metabolism. Biophysical Properties Sphingolipids tend to form clustered structured called microdomains, rafts, or caveolae (when containing caveolin).
Sphingolipid | Membrane Structure, Signaling & Metabolism
sphingolipid, any member of a class of lipids (fat-soluble constituents of living cells) containing the organic aliphatic amino alcohol sphingosine or a substance structurally similar to it. Among the most simple sphingolipids are the ceramides (sphingosine plus a fatty acid), widely distributed in small amounts in plant and animal tissues.
Functions of Sphingolipids in Pathogenesis During …
Aug 1, 2021 · Sphingolipids are a class of membrane lipids that serve as vital structural and signaling bioactive molecules in organisms ranging from yeast to animals. Recent studies have emphasized the importance of sphingolipids as signaling molecules in the development and pathogenicity of microbial pathogens including bacteria, fungi, and viruses.
- Some results have been removed