Acute on Chronic Liver Failure - StatPearls - NCBI Bookshelf
Apr 13, 2023 · Acute on chronic liver failure (ACLF) is a clinical syndrome of sudden hepatic decompensation observed in patients with pre-existing chronic liver disease and associated with one or more extrahepatic organ failures and increased mortality.
Acute-on-Chronic Liver Failure | New England Journal of Medicine
May 27, 2020 · Acute-on-chronic liver failure is a syndrome that affects patients with chronic liver disease; is characterized by intense systemic inflammation, organ failure, and a poor prognosis; and...
Acute-on-chronic Liver Failure and the Management - AASLD
Acute-on-chronic Liver Failure and the Management. This document from the American Association for the Study of Liver Diseases (AASLD) serves to provide guidance and a data-supported approach for the diagnosis, evaluation, and management of patients with cirrhosis and ACLF as well as cirrhosis and critical illness.
Acute-on-Chronic Liver Failure Clinical Guidelines - LWW
If precipitating events, such as viral hepatitis, drug-induced liver injury, and alcohol-related hepatitis, are superimposed on chronic liver disease, the result may be hepatic and extrahepatic organ failure, termed acute-on-chronic liver failure or ACLF.
EASL Clinical Practice Guidelines on acute-on-chronic liver ...
Jun 24, 2023 · Acute-on-chronic liver failure (ACLF), which was described relatively recently (2013), is a severe form of acutely decompensated cirrhosis characterised by the existence of organ system failure (s) and a high risk of short-term mortality.
Acute-on-chronic liver failure: far to go—a review
Jul 1, 2023 · Acute-on-chronic liver failure (ACLF) has been recognized as a severe clinical syndrome based on the acute deterioration of chronic liver disease and is characterized by organ failure and high short-term mortality.
Acute-on-chronic liver failure: Terminology, mechanisms and ...
Acute-on-chronic liver failure is an acute deterioration of liver function manifesting as jaundice and coagulopathy with the development of ascites, with a high probability of extrahepatic organ involvement and high 28-day mortality.
Acute-on-chronic liver failure - PMC - PubMed Central (PMC)
Acute-on-chronic liver failure (ACLF) is a recently recognised and defined syndrome seen in patients with liver cirrhosis and carries a high short-term mortality in excess of 15% at 28 days. ACLF is defined by organ failures (OFs) and is distinct from …
Acute-on-chronic liver failure: recent update - PMC
Acute on chronic liver failure (ACLF) was first described in 1995 as a clinical syndrome distinct to classic acute decompensation.