Idoxuridine (brand names Dendrid®, Herplex®, Stoxil®) is an antiviral topical medication used to treat viral infections of the eye, such as feline herpesvirus-1 (FHV-1) in cats. It may also be useful for treating canine herpesvirus-1 in dogs and equine herpesvirus-2 in horses.

Jul 12, 2022 · Idoxuridine is a topical antiviral cytotoxic agent that is prescribed to treat cats with corneal or conjunctival diseases attributed to feline herpes virus (FHV). FHV can cause several eye problems including corneal ulcers, chronic conjunctivitis, tear duct blockage or infection, keratitis, and inflammation of the anterior chamber of the eye.

Idoxuridine (IDU) is a nonspecific inhibitor of DNA synthesis, affecting any process requiring thymidine. Therefore, host cells are similarly affected, systemic therapy is not possible, and corneal toxicity can occur. It has been used as an ophthalmic 0.1% solution or 0.5% ointment.

Idoxuridine, also known by the names Stoxil®, Herplex®, Dendrid®, is often used for cats in the treatment of conjunctival and corneal disease associated with feline herpes virus. A virus is a packet of genetic material, often DNA, surrounded by a viral envelope or membrane.

Idoxuridine (IDU) acts via a similar mechanism as TFU and is similarly toxic if given systemically. However, it has been used as an ophthalmic 0.1% solution or 0.5% ointment. This drug is well tolerated by most cats and seems efficacious in many. It should be …

In the more severe conjunctivitis cases or whenever the cornea is compromised, topical antibiotics are essential to help prevent secondary bacterial infection; oxytetracycline, erythromycin ointment, or tobramycin drops q8h are good first-line choices.

Medications currently used to prevent viral replication include: l-lysine (Viralys); trifluridine (Viroptic); idoxuridine; interferon alpha; famciclovir (Famvir); and, cidofovir (Vistide).

Feline herpesvirus type 1 (FHV-1) is the most frequent cause of conjunctivitis and keratitis in domestic cats.

Idoxuridine is a topical antiviral drug used to treat ocular herpetic lesions in cats. It is virustatic rather than virucidal. The substitution of idoxuridine for thymidine in the viral DNA causes a misreading of the genetic sequence and consequently the virus is unable to replicate.

Mar 16, 2023 · Topical ocular antiviral therapy: These anti-herpes drugs, known as idoxuridine, trifluridine, and cidofovir, can be used as eye drops in treating cat herpes. Eye drops are usually given...