Nov 13, 2024 · The 54th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2025) will be held from Sunday through Thursday, June 15-19, 2025, in Bruges, Belgium.

Jan 1, 2017 · Figure 1: Simulated chromatograms for a mixture of six neutral compounds (unlabeled peaks between approximately 3 and 9 min) and two carboxylic acids at (a) pH 7.0 and (b) pH 3.0. The peak at approximately 0.75 min is t 0.. When ionizable analytes are present, dramatic changes in retention can take place when the mobile-phase pH is altered.

Practical advice, tutorials, and peer-reviewed research on liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS) and related techniques.

Jul 1, 2009 · Figure 1 The ΣRE data of Table II summarize the data of Figures 1 and 2. For set 1, the ΣRE drops from no weighting (12.23) to 1/x 0.5 weighting (3.39), then it levels off for additional weighting (not shown larger than 1/x 3).These results also suggest that 1/x 2 is the simplest model that adequately describes the curve.

LCGC International spoke to Michelle Klein from the Faculty of Chemistry of the University of Duisburg-Essen (Essen, Germany) about how, by using the green analytical chemistry tool Analytical GREEnness (AGREE) and the white analytical chemistry (WAC) framework, her team was able to conduct a comparative analysis of gas chromatography-tandem mass spectrometry (GC–MS/MS), liquid ...

Jan 1, 2019 · Founded in 1983, LCGC International is the leading provider of digital and print content to the separation science market, enhancing the productivity, efficiency, and the overall value of separation techniques globally. With our commitment to editorial excellence, we have pioneered innovation across a broad portfolio of digital and print platforms.

Jun 10, 2024 · Case Studies from an Early-Phase Small-Molecule Development Project: Background Information. A case study from my experience as a chemistry, manufacturing, and controls (CMC) analytical team lead supporting an early-phase small-molecule oncology drug development project was used to illustrate how CoAs expedite quality documentation of testing methods and results.

Practical advice, tutorials, and peer-reviewed research on liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS) and related techniques.

Jun 1, 2012 · Figure 1: Calibration plots of concentration of analyte (CA) versus response (RA) for external standardization (plain text) and concentration ratio (CA/CIS) versus response ratio (RA/RIS) for internal standardization (labels in parentheses).

Jul 1, 2019 · The invention of the electron capture detector (ECD) is attributed to Lovelock in 1957 (1). The detector measures the electrical conductivity of an effluent gas stream resulting from exposure to ionizing radiation from a radionuclide.