The human immune system is a complex network of cells and signals that guards against disease, yet in the case of cancer, it often struggles to mount an effective response. Recent research, published ...

VD inhibits of Th1 cell differentiation and the production of Th1-specific cytokines. VD facilitates Treg cell generation and activity. VD has a role in the prevention of autoimmune diseases such ...

like anti-nuclear antibodies (ANAs) in SLE and anti-citrullinated peptide antibodies (ACPA) in RA, can be found in >95% and 70% of patients, respectively (164, 165). CD4 + T cells are a heterogeneous ...

After encountering antigen in the periphery and under the influence of the cytokine milieu present, CD4 + T cells can further differentiate into subtypes, including Th1, Th2 and Th17. T cells seem ...

Clinical studies (completed and with published results) for T1D treatment based on cells with regulatory properties including Tregs, tolerogenic DCs ... in terms of more efficient suppression of Th1 ...