and their diversity of functions has led to the hypothesis that an "RNA world" may have preceded the evolution of DNA and proteins (Gilbert, 1986). Small interfering RNAs (siRNAs) are yet another ...
Other classes of RNA species include microRNAs, small interfering RNAs, and sRNAs—all of which are not translated into proteins but still perform important functions in the cell. The discovery ...
Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA.
These small RNAs can bind to complementary mRNA sequences, triggering their degradation or preventing their translation. RNAi is a powerful tool for studying gene function and has potential ...
A study published in PNAS reveals how a bacterial pathogen coordinates N-acetylneuraminic acid (Neu5Ac) metabolism at the ...
Surprisingly, this family has been robustly identified as novel RNA-binding proteins in numerous crosslinking studies. Subsequent validation of these interactions and the additional observation that ...
Ribosomes are composed of two subunits, the small and large subunits ... forming domains and motifs that are essential for ribosome function. The rRNA structures also provide binding sites for ...