RAF, PI3K and the RAL guanine exchange factor (RAL ... and NF-κB activation are required for KRAS-induced tumorigenesis. Autophagy counterbalances cellular stress associated with oncogenic ...

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Its involvement in key pathways like PI3K/Akt/mTOR and its regulation of oncogenes such as MYC and β-catenin further emphasize the importance of context when evaluating FTO’s function in various ...

including nuclear factor erythroid 2-related factor 2 (Nrf2), nuclear factor kappa-B (NF-κB), phosphatidylinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR), ...

This cover highlights the article Deciphering the molecular logic of WOX5 function in the root stem cell organizer by Ning Zhang, Pamela Bitterli, Thomas Laux and colleagues. The image highlights the ...