First described by Charcot over 125 years ago, the primary characteristic of this disease is the selective degeneration of upper and lower motor neurons, initiating in mid-adult life and almost ...

The disease process is characterized by axonal retraction and the subsequent loss of upper and lower motor neurons. This animation focuses on the mechanisms that drive ALS pathogenesis.

AUTS2 syndrome patients often exhibit microcephaly, yet its etiological mechanism remains unclear. This study reveals that ...