First described by Charcot over 125 years ago, the primary characteristic of this disease is the selective degeneration of upper and lower motor neurons, initiating in mid-adult life and almost ...

This important study conducted experiments to quantify how changes in blood flow results in apparent fluorescence changes when imaging neural activity sensors using two-photon microscopy. While the ...

AUTS2 promotes IPC division and production of upper-layer neurons by suppressing Robo1 expression. Loss of Auts2 results in increased Robo1 expression, lower levels of IPC division, and decreased ...

During the development of the olfactory epithelium (OE), olfactory sensory neurons (OSNs) express only one member of the odorant receptor (OR) gene family, and O ...

Abstract: Amyotrophic lateral sclerosis (ALS) is a chronic, progressive neurodegenerative disease that mainly causes damage to upper and lower motor neurons. This leads to a progressive deterioration ...

Men with SMA are likely to have fertility issues, and patients with more severe motor impairments have lower sperm counts, ...

Age is an issue of mind over matter — h/t Mark Twain — but early ALS clinical trial results from Google-backed aging-disease ...

There are simple ways to stave off health problems - and enjoy a life rich in vitality and purpose. Start by walking up hills ...

His growth was stunted from the lack of ability to strengthen his lower limbs, and his upper body became overdeveloped ... Polio destroys the motor neurons, but the sensory nerves are not affected ...

By one estimate, 68% of Americans consume less than the recommended dietary amount of magnesium. Magnesium is essential for ...