New Method Detects Ligand-Protein Interactions With Unprecedented Sensitivity
PELSA is a sensitive, versatile method for identifying ligand-binding proteins and sites in native systems without requiring ...
C&EN4d
RNA aptamers light up after ligand reacts
Researchers have tested strategies to combine riboswitches—RNA motifs that change conformation in response to binding another molecule—with these aptamers to create biosensors that fluoresce only when ...
SciELO10d
Severe murine schistosomiasis results from disrupted CD4+ T-cell modulation by immunodominance of a single egg epitope
While the exact mechanisms linking ID to modulation remain to be fully elucidated, both are influenced by three common components: epitope availability, epitope affinity for the MHC and epitope ...
Armed robbery in Revesby13d
Immutep, Monash Reveal LAG-3 Binding to MHC Class II
Clinical-stage company Immutep (ASX:IMM) has announced new findings published in Science Immunology that resolve how human ...
Immutep, Monash University announce publication on human LAG-3
Immutep (IMMP) announces new findings published in Science Immunology that resolve how human lymphocyte activation gene 3 binds to its main ...
Morningstar14d
Immutep and Monash University Announce First Publication Detailing How Human LAG-3 Binds to MHC Class II
Findings published in Science Immunology resolve how human LAG-3 binds to its main ligand providing a ... preferential binding to a subset of MHC Class II molecules on antigen-presenting cells ...
Frontiers16d
Myeloid antigen-presenting cells in neurodegenerative diseases: a focus on classical and non-classical MHC molecules
Antigen-presenting myeloid cells display different classes of major histocompatibility complex (MHC) and MHC-like proteins on their surface for presenting various types of antigens to a wide variety ...