PELSA is a sensitive, versatile method for identifying ligand-binding proteins and sites in native systems without requiring ...
Researchers have tested strategies to combine riboswitches—RNA motifs that change conformation in response to binding another molecule—with these aptamers to create biosensors that fluoresce only when ...
The Discovery of New Members of the TNF Receptor and Ligand Families and Their Relationship to Osteoclasts and Bone Metabolism Binding of RANKL to RANK initiates a signaling cascade, which ...
What is the current share price of Manhattan Corporation Limited (MHC)? Manhattan Corporation Limited's (MHC) current share price is $0.02. This constitutes a price movement of 4.55% when compared to ...
Controversy exists as to the role that the immune system plays in cancer therapy. While the immune system has been proposed to scavenge the body to prevent microscopic transformation from forming ...
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Objectives Rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS) share many clinical manifestations and serological features. The aim of this study was to ...
To this end, we designed, synthesized, and evaluated a series of potent heterobifunctional TEAD-CIDEs based on reversible TEAD lipid pocket binding ligand Compound A. As a proof-of-concept study, we ...