A mathematical model suggests that existing HPA-targeting drugs failed in clinical trials for mood disorders because the ...

Glucagon-like peptide 1 receptor agonists (GLP1RA)—medications for type 2 diabetes and obesity that have recently been making ...

A breakthrough study sheds new light on how brain cells relay critical information from their extremities to their nucleus, leading to the activation of genes essential for learning and memory.

It is useful to distinguish between general attenuation, which functions at the level of the ligand–receptor complex, and pathway-specific inactivation (for example, inactivation of SOS through ...

Department of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States Institute for Drug and Biotherapeutic Innovation, Saint Louis University, Saint Louis, Missouri 63103, ...

Swing by our New Arrivals shop, and then check out what our editors are buying right now. In the GQ offices, celebrating the new year involves more than just champagne and resolutions: it means a ...

TGFβs initiate diverse cellular responses by binding to and activating specific type I and type II Ser/Thr kinase receptors and ... cancer by modulating this pathway in the tumour vasculature.

Pattern recognition receptors that specifically bind to and get activated by DNA such as Toll-like receptor-9 (TLR9), cyclic GMP-AMP synthase (cGAS), Nod-like receptor protein 3 (NLRP3) and Absence in ...