Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

Gerry Baker is Editor at Large of The Wall Street Journal. His weekly column for the editorial page, “Free Expression,” appears in The Wall Street Journal each Tuesday. Mr. Baker is also host ...

We list the best free Adobe Illustrator alternatives, to make it simple and easy to manage graphics files without a Creative Cloud subscription. We've rounded-up our top-rated choices for when you ...

Reliable tools for detecting ISR activation in situ are lacking, so this manuscript describes a potentially valuable tool that builds on and overcomes some of the limitations of a similar viral vector ...

The second vaccine, VRC 303, an improved version of VRC 302, used a modified promoter (CMV/R) to enhance protein expression. In a phase I trial (NCT00300417), it induced strong neutralizing antibody ...

In this study, a metagenomic fosmid library was functionally screened for chitinase activity, and a chitinase coding gene, named metachi18A, was identified and cloned into an expression vector. The ...

Department of Engineering Science, University of Oxford, Oxford OX1 3PJ, U.K.

Department of Life Sciences, Imperial College London, South Kensington, London SW7 2AZ, U.K. Imperial College Centre for Synthetic Biology, Imperial College London, South Kensington, London SW7 2AZ, U ...