Immunopathologies encompass a range of conditions known for their defined pathophysiology but lack safe and effective treatment options. These diseases ...

Discover the potential of macrocycles in drug discovery: flexible, cell-permeable molecules targeting undruggable proteins.

Scientists have long considered ketones (a fundamental chemical class) and esters (molecules formed when an acid reacts with an alcohol) to be locked treasure chests of possibilities. Ubiquitous as ...

“We are proud that our advanced modeling and simulation software and consulting services supported the development of the ...

Inhibition of group IVA cytosolic phospholipase A2 (cPLA2α) is a potential approach for cancer treatment. Here, the authors report thiazolyl ketone inhibitors of cPLA2α starting from compound ...

Nearly half of India's 10,000 drug manufacturing units might not meet the 2025 deadline for upgrading to revised Schedule M standards, risking closure. Currently, only 2,000 comply with good ...

While the New Year's tradition of drug price hikes has held firm for ... stressed that the increases support investments in drug development. Bristol Myers Squibb, for its part, has raised the ...

executive vice president and head of research and development at Neumora, said in a statement. Lenz noted the “contrast” in drug and placebo responses in depressed mood and anhedonia in female ...

State Key Laboratory of Anti-Infective Drug Discovery and Development, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China ...

She said the increases help support investments in drug development and offset costs. Bristol Myers raised the price of its expensive cancer cell therapies Abecma and Breyanzi by 6% and 9% ...

The parliamentary standing committee on chemicals and fertilisers has highlighted a concerning 5.9% conviction rate for spurious or adulterated drug cases in India. From 2015-19, 593 drug samples were ...

Scientists discover a 'Goldilocks' zone for DNA organization, opening new doors for drug development. ScienceDaily . Retrieved January 20, 2025 from www.sciencedaily.com / releases / 2024 / 12 ...