Tissue samples from the injection sites were collected for immunofluorescence and immunohistochemical ... While YAP/TAZ directly inhibits PPARγ, potential crosstalk with Wnt/β-catenin or AMPK pathways ...

At the forefront of this revolutionary approach is a team of Canadian researchers who uncovered how low AMPK levels correlate with weight gain—often overshadowing the traditional “eat less ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Bladder cancer is one of the most common malignant tumors of the urinary system globally. It is also one of the most expensive cancers to manage, due to the need for extensive treatment and follow-ups ...

This important study provides insights into the physiological role of RIPK1 in liver physiology, particularly during short-term fasting. The discovery that RIPK1 deficiency sensitizes the liver to ...

Finally, we performed the qualitative immunofluorescence analysis of β1AR and GluA1, as well as colocalization analysis of β1AR–GluA1, to identify FC regions where these two receptors might interact.

Clinical Physiology provides diagnostic methods to detect and evaluate dysfunction of various organs and systems in the body such as the heart, peripheral vessels, lungs, kidneys, gastrointestinal ...

In this study, we demonstrate the feasibility of generating virtual stains for hematoxylin and eosin (H&E) and a multiplex immunofluorescence (mIF) immuno-oncology panel (DAPI, PanCK, PD-L1, CD3, and ...

Could nanotechnology improve exercise performance? Evidence from animal studies Lima, M.R. Moreira, B.J. Bertuzzi, R. Lima-Silva, A.E.