Intravenous voriconazole was administered in 6 cases. In one patient, 0.6-1.5 mg/L had been the usual voriconazole trough concentration; however, 12 hours after the last dose, the concentration ...

There was a high degree of variability in voriconazole drug levels among patients (r 2 = 0.01; range, <0.10 - 20 mg/L). Of the 46 patients with proven or probable invasive fungal disease ...