Neurosyphilis was diagnosed in 50 of 233 HIV-coinfected subjects (about 20%) on the basis of a reactive CSF VDRL in 16 patients, a CSF WBC count >20 cells/mm 3 in 22, and both of these ...

This type of abnormal fluid is of considerable prognostic significance in the development of future parenchymatous neurosyphilis. Intensive therapy, occasionally reinforced by fever, is necessary ...