A total of 1,091 patients with type 2 diabetes and HbA 1c levels of 7.5–11.0% were randomly assigned to receive combination therapy with daily sitagliptin (100 mg) and metformin (either 1,000 mg ...

Recently, the US FDA approved initial combination therapy with sitagliptin and metformin (Janumet™) in order to help more patients with Type 2 diabetes mellitus get closer to accepted glycemic ...

to achieve plasma concentrations of sitagliptin similar to those in patients with normal renal function, a dosage adjustment is recommended for patients with moderate renal insufficiency (50 mg ...