Cellular senescence, where cells permanently stop dividing, plays a complex role in liver health. In a recent review article, ...

In the right column, the protein detected (p21-Cre) is only expressed in senescent liver cells ... cause DNA damage in liver cells that causes them to go into senescence, a state in which cells are ...

However, the role of p21 cells in wound healing is largely unknown ... to others in the field about the diversity of cellular senescence and the importance of thoroughly evaluating the roles ...

Gut microbiota-derived phenylacetylglutamine accelerates aging by driving cellular senescence through mitochondrial ...

While cellular senescence can serve protective functions ... still ill-identified—showing an increased marker known as p21 but independent from p16,” Bartolomucci explained.

There, he contributed to define the involvement of p53, p21 and reactive oxygen species in senescence. Since 2008, he is the head of the Mechanisms of Cancer and Ageing Lab at the University of ...