carinii infection at oral daily doses of 2.25 mg/kg. The authors concluded that although caspofungin acetate was ineffective in reducing the trophozoite form, its use as P. carinii prophylaxis ...

The Phase 1 trial is a randomized, double-blind, placebo-controlled study of single and multiple ascending doses of oral SCY-247 in approximately 100 healthy subjects. The primary endpoint is safety ...