Selenium-containing glutathione peroxidase (GPX) Protects cells from hydrogen peroxides and lipid hydroperoxides. If not neutralized, these peroxides will damage cellular membranes and other vital ...
Ebselen is under clinical development by Sound Pharmaceuticals and currently in Phase II for Drug Toxicity. According to GlobalData, Phase II drugs for Drug Toxicity have a 65% phase transition ...
Among these, the selenoenzyme glutathione peroxidase 4 (GPX4) stands out, playing a key role in preventing ferroptosis by protecting cells against damaging (phospho)lipid peroxidation. The team ...