Interpatient absorption variability was approximately 30% BSV for all absorption parameters. Intranasal versus intravenous administration ... sigmoid maximum drug effect dynamic model.

Passive diffusion plays an essential role in oral absorption of drugs through the gastrointestinal tract, penetration across the blood-brain barrier to reach Central Nervous System disease targets, ...

GERD: Inject IV over ≥3 mins or infuse IV over ... May potentiate saquinavir; monitor for toxicity. May reduce absorption of gastric pH-dependent drugs (eg, iron salts, erlotinib, dasatinib ...

Alternative dosing routes, such as rectal and intranasal (IN) routes, have been suggested as options for oral or intravenous ... the rate and extent of absorption of drugs administered by the ...

The U.S. Food and Drug Administration said on Friday that it has approved an injectable version of Bristol Myers Squibb's ...