Recent research has significantly advanced our understanding of the various subsets of dendritic cells and their specific roles in modulating T cell responses, especially in the tumor ...

In addition, in MDS, naive T-cell polarization by different DC subsets may play an important role. It can be hypothesized that DCs instruct T cells to a Th1 response in low-risk disease ...

Dendritic cell vaccines can be generated via ex vivo differentiation ... subsequent expression of CTLA-4 and AIMp1 as well as the resultant T cell responses observed. A novel subset of cytotoxic ...