Researchers from the Mattiroli group have found that the way DNA is packaged in cells can directly impact how fast DNA itself ...

These CENP-A proteins ensure that divided genetic information is kept intact during mitosis.

Gene mutations have consequences both good and bad—from resistance to conditions like diabetes to susceptibility to certain ...

Membraneless organelles, also called biomolecular condensates, are changing how scientists think about protein chemistry, ...

Harvard researchers pioneered a method called HACE for targeted gene mutations, advancing genetic research potential.

This important work advances our understanding of DNA methylation and its consequences for susceptibility to DNA damage. This work presents evidence that DNA methylation can accentuate the genomic ...

Altered activity of ancient viral genes were linked to neurodegenerative diseases including ALS in a recent analysis.

Those featured circles, ecDNAs, are small and often contain a few genes on their circular DNA. Frequently, these genes are cancer-associated genes called oncogenes. When a cancer cell contains ...

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...

"Our finding fundamentally alters our understanding of how cells are organised," explains Dr. Pardo Lorente. "The nucleus isn't just a passive storage space for DNA; it has its own metabolic needs and ...

Researchers have found that the way DNA is packaged in cells can directly impact how fast DNA itself is copied during cell division. They discovered that DNA packaging sends signals through an unusual ...

It tells the cell how, where and when to 'read' and use the information in the DNA. It is important that both the DNA and its chromatin are copied accurately to ensure young and healthy cells .