The objectives of this study were to develop and test an adjustment factor (AF) for estimating aminoglycoside clearance (CL amino) from the Cockcroft–Gault equation in underweight patients and ...
The common use of the Cockcroft-Gault equation suggests that it will remain the method of choice for drug dosing in patients with renal impairment. In contrast, the MDRD4 equation is likely to ...
Results were similar if the Cockcroft–Gault formula was used to calculate eGFR. Importantly, the study also found that the risk of cardiovascular and renal events was higher in patients with ...
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