Bisphosphonates are the mainstay of osteoporosis therapy. Extensive clinical evaluation supports their utility in stemming progression of the disease and in reducing fracture risk. In the course ...

Atypical femoral fractures (AFFs) are a rare type of bone fracture that can occur in patients taking bisphosphonates, a class of medications commonly used to treat osteoporosis. These fractures ...

The bisphosphonates Aredia and Zometa and the monoclonal antibody denosumab can reduce the risk of fractures. Both classes of medications carry a small risk of osteonecrosis of the jaw. A dental ...