Lithocholic acid is one such secondary metabolite, made by gut bacteria from a bile acid produced by the host. But the idea ...

Conclusion: The low blood levels of LCA found indicate a normal metabolism of this bile acid in fetuses with EHBA. The increased levels of CA and CDCA in the infants with this disease can be due ...

In the short term, we hope to improve our understanding of bile-acid signalling and metabolism and show how MCBAs interact with and affect the host. The broader, long-term goal is to use this ...

Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may affect ...

These effects were achieved by interfering with the PPARα signaling pathway and promoting the synthesis of hydrophilic bile acids. “A remarkable breakthrough is the demonstration that the inhibition ...

These effects were achieved by interfering with the PPARα signaling pathway and promoting the synthesis of hydrophilic bile acids. A remarkable breakthrough is the demonstration that the ...