Typical Antipsychotics, or First Generation Antipsychotic Drugs. The typical, or conventional, antipsychotics were first developed in the 1950s. Haldol (haloperidol) and Thorazine (chlorpromazine ...

Insurer access challenges likely lie ahead for the novel schizophrenia drug Cobenfy, given its considerably higher price than ...

Mechanisms of Q-Tc Interval Prolongation with Antidepressants and Antipsychotics Crumb and colleagues ... Though these drugs had little direct effect on cardiac ion channels, the effects that ...

Addition of the antipsychotic lumateperone (Caplyta) to an existing antidepressant improved symptoms of depression in a ...

Antipsychotic drugs are effective in relieving positive symptoms of psychosis including AVHs, but the mechanisms of action are only fragmentarily understood. Pharmacological fMRI may reveal ...

last week approved Bristol Myers Squibb’s antipsychotic drug Cobenfy (xanomeline and trospium chloride), the first ...

antipsychotic, and anti-nausea medications) but drugs with other mechanisms of action can also cause tardive syndrome. This group of disorders is often referred to in the literature as “extrapyramidal ...

Karuna Therapeutics said this morning that the FDA has formally started its review of KarXT, aiming to become the first drug to reach the market for schizophrenia with a new mechanism of action in ...

The mechanism of action of clozapine ... Caution with concomitant drugs known to prolong the QT interval: certain antipsychotics (eg, ziprasidone, iloperidone, chlorpromazine, thioridazine ...