(3) This causes synaptic vesicles to fuse with the terminal membrane, releasing neurotransmitter into the gap between neurons, known as the synaptic cleft. (4) The neurotransmitters bind to ...

Introduction of Snapin–CT and peptides containing the SNAP–25 binding sequence into presynaptic superior cervical ganglion neurons in culture reversibly inhibited synaptic transmission.

Synaptic transmission is an energy hog. It requires neurons to tap ATP reserves to respond to incoming signals. How do they pull this off, thousands to millions of times per day? A new study ...