Venafro is a comune in the province of Isernia, region of Molise, Italy. It has a population of 11,079, having expanded quickly in the post-war …Venafro is a comune in the province of Isernia, region of Molise, Italy. It has a population of 11,079, having expanded quickly in the post-war period. Situated at the foot of Mount Santa Croce, elevation 1,026 metres above sea level, at a height of 222 metres above sea level, the elevation of the municipal territory varies from 158 to 1,205 metres above sea level. The municipality stretches along the homonymous plain crossed by the Volturno and San Bartolomeo rivers whose sources are located in the center of the Venafro plain. Other notable mountains are: Monte Sambucaro at 1,205 metres, Monte Cesima at 1,180 metres, Monte Corno at 1,054 metres, Monte Santa Croce or Cerino, at 1,026 metres, and Colle San Domenico at 921 metres. Once a part of the province of Terra di Lavoro in Campania, the city is now known as the door of Molise and is of major importance to the socio-economic dynamics of the province due to its highly developed economy, and is considered one of the four central industrial cores in the region.