Blackburn is a city in Lafayette and Saline counties in the U.S. state of Missouri and is part of the Kansas City metropolitan area. The popula…Blackburn is a city in Lafayette and Saline counties in the U.S. state of Missouri and is part of the Kansas City metropolitan area. The population was 224 at the 2020 census. Blackburn was platted in 1880 when the railroad was extended through the neighborhood. A post office called Blackburn has been in operation since 1878. The community shares a name with a town in Lancashire England and has the name of Francis Blackburn, a first settler.